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Medical Information:

Ezetimibe (e-ZET-e-mibe) is used to lower cholesterol and triglyceride (fat-like substances) levels in the blood. Using this medicine may help prevent medical problems caused by such substances clogging the blood vessels.

Ezetimibe is a new kind of cholesterol-lowering drug. The older cholesterol-lowering drugs called "statins" reduce cholesterol by interfering with its production in the body. Zetia acts by diminishing the absorption of dietary cholesterol through the intestines.

Ezetimibe may be taken alone or with a statin drug. Because the two drugs fight cholesterol in different ways, the Ezetimibe/statin combination has a greater impact than either drug alone.

Cholesterol--especially "bad" LDL cholesterol--promotes clogged arteries, increasing the risk of heart attack and stroke. "Good" HDL cholesterol helps to prevent clogged arteries. Zetia lowers the bad cholesterol and raises the good. It also lowers total cholesterol readings and reduces levels of triglycerides (fats in the blood).

Cholesterol-lowering drugs are typically prescribed for people who either have heart disease or are in danger of developing it. For people at high risk of heart disease, current guidelines call for considering drug therapy when LDL levels reach 130. For people at lower risk, the cut-off is 160. For those at little or no risk, it's 190.Inhibits absorption of cholesterol by the small intestine.Ezetimibe reduces the amount of cholesterol absorbed by the body.